Workshop Agenda: 

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October 29, 2004 (Friday):

Noon-5:00 pm          Registration and assignment to Panel Discussion Groups 1, 2 or 3.
   Coordinators: Kathy Lau and Janet Ireland

5:00-6:30 pm              Session I: Welcome to Michigan State University and keynote
               address:   Chairs: Dr. Mark Mirando (USDA-CSREES), Dr. Lou    

                                       DePaolo (NICHD)

5:00-5:30 pm              Welcome

   Dr. Lou Anna K. Simon, Provost and President-Designate,

   Michigan State University

5:30-6:30 pm              Keynote address

   Are the Domestic Farm Species Redundant as Models in Biomedical
               Research? Does Mighty Mouse Rule Supreme?

   Dr. R. Michael Roberts, University of Missouri.

6:30-7:30 pm              Cash bar and hors d'oeuvres 

7:30-9:00 pm              Dinner

                                       Welcome to Michigan State University, Dr. Jeffrey Armstrong,
                                       Dean, College of Agriculture and Natural Resources, MSU

October 30, 2004 (Saturday):

6:30-8:00 am              Continental breakfast

8:00-10:00 am            Session II:   Reproductive Physiology & Developmental

                                       Biology: Chairs:  Dr. Debora Hamernik (USDA-CSREES) and

                                       Dr. Lou DePaolo (NICHD)

  Speakers:

  Prenatal programming of reproductive and metabolic dysfunction:

  the sheep as a model

  Dr. Vasantha Padmanabhan, University of Michigan   [Abstract]

  The Chicken -  A valuable model for investigations in reproductive

  biology and reproductive diseases
  Dr.  Janice Bahr, University of Illinois   [Abstract]

  Swine as biomedical models

  Dr.  Randy Prather, University of Missouri   [Abstract]

10:00-10:15 am         Break and refreshments

10:15-12:15 pm        Session III:   Health and Disease:  Chairs: Dr. Bradley Fenwick
                                     (Vice President for Research, Virginia Polytechnic Institute and University)                                     

 and Dr. John Baker (Interim Director, Agricultural Experiment Station,
             Michigan State University)

  Speakers:

  Use of cattle to study the immunobiology of γδ T cells

  Dr.  Mark Jutila, Montana State University   [Abstract]

  Understanding pathogen transmission in emerging infectious disease

  Dr.  Guy Palmer, Washington State University   [Abstract]

  Porcine models in the study of cardiovascular effects of exercise in

  health and disease

  Dr.  Harold Laughlin, University of Missouri   [Abstract]

12:15–1:00 pm          Lunch

1:00-3:00 pm             Session IV: Advanced Technology and Genomics: Chairs: 

                                      Dr. Daniel Schmoldt (USDA-CSREES) and Dr. Paul Coussens

                                      (Michigan State University)

  Speakers:

  Microbial pathogenomics
  Dr. Vivek Kapur, University of Minnesota   [Abstract] 

  New approaches to the prevention of sudden cardiac death: validation
  in canine and porcine models

                                      Dr. Robert Gilmour, Jr., Cornell University   [Abstract]

                                      Nuclear transfer cloning of cattle: a model system for studying the
                                      genomic biology of totipotent stem cells

  Dr. Harris Lewin, University of Illinois   [Abstract]

3:00-3:15 pm             Break and refreshments

3:15–5:15 pm           Session V:  Nutrition: Chairs: Dr. Etta Saltos (USDA-CSREES)

                                     and Dr. Pam Starke-Reed (NIH, DNRC)

  Speakers:

  The pig and sheep as animal models for nutrition research
  Dr.  Guyao Wu, Texas A&M University   [Abstract]

  Nutritional biochemistry of the developing neonate: Insights gleaned

  from a piglet model

  Dr.  Jack Odle, North Carolina State University   [Abstract]
 

  Pre- and post-natal influences on adipose tissue development and
  metabolism: the pig as a model
  Dr. Dorothy Hausman, University of Georgia, Athens   [Abstract]

5:30-7:00 pm             Dinner

7:00–9:00 pm            Multiple Breakout Sessions I:  Moderators:  Group 1 – Dr. Debora

                                      Hamernik (USDA); Group 2 – Dr. Fuller Bazer (Texas A & M);

                                      Group 3  – Dr. Louis DePaolo (NICHD)

Questions to address:  

·        What are the important research areas in human health not identified by
 speakers that could be advanced by use of domestic species as biomedical
 models? 

·        Are there any real or perceived “barriers” using domestic species as models for
 biomedical research? 

·        In what ways will the new knowledge generated during the genomics era of
 research in digestive, reproductive, immune, and other systems benefit both
 animal agriculture and human medicine?

·        Is justification for use of domestic animals as models for biomedical research
 more difficult compared with rodent models?  If so, why?

9:00-11:00 pm            Social and cash bar

October 31, 2004 (Sunday):

6:30-8:00 am              Continental breakfast

8:00-10:00 am            Multiple Breakout Sessions II:  Moderators:  Group 1 – Dr. Debora

                                       Hamernik (USDA); Group 2 – Dr. Fuller Bazer (Texas A & M); 

                                       Group 3 – Dr. Louis DePaolo (NICHD)

Questions to address:

·        What is needed to enhance the use of domestic species as biomedical models?
For example, in the current funding systems, what processes should be kept,
discarded, or created to enhance the use of domestic animals as biomedical
models?  What would the future look like if the use of domestic species for
biomedical research were not enhanced?   What is the desired (and realistic)
outcome/expectation for the use of domestic animals as biomedical models? 
What are the major constraints/barriers to achieving these goals? 

·        Should strategies to address the issues raised in Question 1 (Breakout Session II)
be developed, and if they are developed, such as in a “white paper”, what is the
likelihood that they will enhance use of domestic species as biomedical models by
2010?  Who will develop and implement these strategies?

·        How could greater cooperation between medical schools and animal science
departments to use domestic species as biomedical models be fostered?       

10:00-10:30 am           Break and refreshments

10:30–12:30 pm          Final Workshop Summary and Planning Session. Chairs: Dr.

                                        Michael Roberts, University of Missouri; Dr. Bradley Fenwick,

                                        Virginia Polytechnic Institute and State University

    Moderators from each group will present summary of results of Breakout
    Sessions I and II

    Open for any questions/issues

12:30 pm                      Adjourn